Estradiol 0.5mg Tablet
Estradiol is the predominant biologically active estrogen in humans and a critical modulator of reproductive, skeletal, cardiovascular, and neuro-endocrine function throughout adult life.
Estradiol is the predominant biologically active estrogen in humans and a critical modulator of reproductive, skeletal, cardiovascular, and neuro-endocrine function throughout adult life.
When ovarian production declines after natural menopause, bilateral oophorectomy, gonadotoxic chemotherapy, or primary ovarian insufficiency, compounded estradiol capsules prepared under section 503A enable clinicians to restore physiologic hormone concentrations using patient-specific doses and excipient profiles that may differ from commercial tablets.
The compounded formulation employs micronized USP-grade estradiol dispersed in a cellulose base, promoting rapid disintegration and predictable intestinal absorption while avoiding lactose, dyes, or magnesium stearate that can provoke intolerance in sensitive individuals.
| Pharmacy | ProRX |
|---|---|
| Instructions | Store compounded estradiol capsules tightly closed at 20-25 °C (68-77 °F) in a dry, dark location; refrigeration is not necessary. Stability studies demonstrate no significant potency loss for six months when humidity remains below 60%, whereas bathroom storage can soften gelatin shells and degrade active content. Patients should keep bottles in a bedroom drawer or closet and discard any capsules remaining after the beyond-use date on the label. |