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Testosterone Cream, 30mL


Testosterone is the primary androgen in the body that controls growth, development, and function of male sexual organs and characteristics. This is a controlled medication, commonly prescribed for the treatment of low testosterone levels in males (hypogonadism) who do not produce enough natural testosterone. It can also be prescribed in specific adolescent cases to induce puberty in those who are experiencing a delay.

Men frequently experience declines in testosterone levels that correlate with the hormonal changes that women experience at menopause, however, men typically have a slower and more subtle hormonal decline, and develop symptoms over a period of time. When hormones are replaced or restored back to physiologic levels considered normal for younger males, men may experience a dramatic reversal of many of these changes.

In clinical trials, Testosterone Replacement Therapy (TRT) has produced

        - Improvement in psychological well-being and mood.

        - Improvement in erectile dysfunction and libido.

        - Increased muscle mass, strength, and stature.

        - Preservation of bone mass.

Testosterone therapy may not only treat hypogonadism, but may also have tremendous potential to slow or halt the progression from metabolic lsyndrome to overt diabetes or cardiovascular disease via beneficial effects on insulin regulation, lipid profile, and blood pressure.

Natural testosterone must not be confused with synthetic derivatives or "anabolic steroids," which when used by athletes and body builders can cause disastrous effects. Hormone balancing for men may also include HCG, DHEA, and other supplements as well as aromatase inhibitors such as anastrozole and selective estrogen receptor modulators such as tamoxifen and clomiphene.

Cream is applied topically to the skin for transdermal absorption.

Click here to visit our website and read more about our TRT program: 

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Patient Instructions

Applying Topical Hormone Cream: Testosterone cream

-First, wash your hands with soap and water

How to Apply:testosterone cream should be applied once per day unless otherwise instructed by your physician. . 

Where to Apply

  • WOMENTestosterone may be applied to abdomen and inner thighs. or Apply vaginally prior to sexual activity.     
  •  MEN:  Apply to inner thigh, shoulders, upper chest, or inner arm 

** Rotate application sites each day.  If you are only applying the hormone to one area, rotate sides each day (example:  left/right arm) 

Always Remember

  • * Limit your contact with other people or animals for 30min after applying hormone cream.  It is possible to transfer transdermal hormones to others if it is not fully absorbed.
  • * Wash hands immediately after applying hormone cream
  • * Do not mix or layer over other hormone creams or skin lotions
  • * Do not bathe or shower for 40min after applying cream
  • * Do not exercise or promote sweating for 2 hours after application
  • * Always be sure to follow the directions provided by your pharmacy and physician.


Please contact our medical office if you have any questions: 813-445-7342

Topical Hormones: Gels and Creams

Topical hormones come in a variety of dispensing devices. The most common devices include a pump, large syringe, Topi-Click, and single dose packets. When dispensing your hormone gel/cream it is important to understand how much you are supposed to apply.  


Here is a breakdown of how standard dispensing devices measure:

Pump:                  4 pumps = 1 ml

Topi-Click:          4 clicks = 1 ml

Syringe:               Syringes are typically measured in increments so you can measure the amount you dispense by pushing the plunger 1ml. Syringes designed to dispense topical hormones do not require a needle, the cream is dispensed through a nipple at the bottom of the syringe. The syringe plunger is pushed down to dispense the cream in measured doses. Syringes typically have lines marking 1ml measurements and come in various sizes to accommodate dosage amounts. If you need assistance reading the measurements on the syringe contact Defy Medical.

How to convert your hormone strength from % to milligrams.  

Sometimes pharmacists prefer to note the strength of the hormone cream in percentages rather than milligrams (mg). For example, it may be written on the label: Testosterone 10% gel 30ML. This is simply a different way of writing the strength. Here is how it works:  


To convert the % into milligrams simply move the decimal to the right one time.  


5% = 50 mg  

10% = 100 mg  

20% = 200 mg  


Using testosterone 10% gel 30 ML as an example, we can interpret this to mean “testosterone 100 milligrams (mg) per milliliter (ml). There are 30 ml in the order which means you have thirty 100 mg doses. If you are prescribed to “apply ½ ml every day” this means you are applying 50 mg and your 30 ml supply will last 60 days. Remember, the cream is 100 mg per ml and you are applying ½ ml (50 mg). Contact Defy Medical staff if you need clarification on your dosage instructions. 



Store your topical hormones at room temperature. Keep in the original closed container in a dark, cool, and dry place away from children. Discard unneeded medicine. 

Be sure to follow the dosage prescribed by your doctor located on the medication label.  

Topi-Click®  Dispensing Instructions 

 Read all information and instructions carefully before dispensing from the Topi-Click™.  

  1. Pop off the cover by placing thumb in groove on the front where it says REFILL and press upward on the cover’s thumb tab.  

  1. Turn the base slowly as shown below in Fig. 2 to dispense the specified _____ # of clicks per topical provider’s instructions. You may refer to the bottom for reminder instructions. 

  1. Apply by rubbing applicator pad to area of skin as directed by topical provider.  

  1. Replace cover firmly and tightly.    

  1. When the bottom line (see Fig. 5 below) reaches the engraved line above the word “Refill,” it may be time to call in for any refills because there are approximately 12 clicks left.  


The Refill Indicator: There are approximately (depending on viscosities) the following numbers of clicks left when the very bottom of the topical elevator reaches the line engravings on the front; Refer to Fig. 5 below. Look at the top front for these engravings:  


______ = 12 clicks left (first line from the top)     ______ = 32 clicks left (second line from the top)   


Downloadable at

The Topi-Click is a one-time use container and is not refillable.

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