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Tretinoin TAN Sensitive Cream


Tretinoin 0.015%/ Azelaic Acid 4%/ Niacinamide4% 

Tretinoin, or all-trans retinoic acid (ATRA), is a powerful Vitamin A derivative (retinoid). It has anti-aging properties and can help fine lines and skin tone as well as with acne and acne scars, as well as acne and acne scars.

Tretinoin creates its effects by encouraging skin cell turnover, which can help skin look brighter, firmer, and more youthful. Cell turnover can also help clear clogged pores and reduce the appearance of acne and acne scarring.

Defy Medical offers three forms of Tretinoin TAN Cream. If you have delicate skin, the Sensitive Cream is likely a good place to start. If you’re not sure, consider how your skin responds to retinol, since Tretinoin is a more potent Vitamin A derivative than retinol. If you have a strong reaction to retinol, it’s best to start with a Sensitive or Mild Tretinoin cream.


Also known as all-trans retinoic acid (ATRA), Tretinoin is one of the most bioactive forms of retinoids, which are vitamin A derivatives.

Azelaic Acid

Used topically in the management of acne vulgaris and other inflammatory skin conditions such as rosacea, azelaic acid is found naturally in wheat, rye, and barley. It is a straight-chain dicarboxylic acid and can also be produced by Malassezia furfur, otherwise known as Pityrosporum Ovale, which is a species of fungus that is naturally found on human skin. While not very clear, azelaic acid is believed to exert its effects through the inhibition of cellular synthesis in both aerobic and anaerobic bacteria.


Niacin (nicotinic acid or 3-pyridinecarboxylic acid) is a B-complex vitamin. Good dietary sources of niacin are animal proteins, beans, green vegetables, liver, mushrooms, peanuts, whole wheat, and unpolished rice. Niacin is also present in cereal grains but is largely bound to plant proteins, and thus is poorly absorbed after ingestion.

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