LabCorp Test #: 010322, CPT: 84153
Prostate Specific Antigen (PSA) is produced exclusively by cells of the prostate gland. Used in conjunction with the digital rectal exam (DRE), PSA is a useful screening test for benign prostate enlargement, prostatitis, and prostate cancer development. There are some things a man should refrain from before having a PSA test completed. These things are as follows: Refrain from vigorous exercise and activities that stimulate or 'jostle' the prostate, such as bike riding; motorcycling; riding a horse, ATV, or tractor; or getting a prostatic massage for 48 hours prior to test. Do not participate in sexual activity that involves ejaculation for 48 hours prior to test. Ejaculation within this time frame may affect PSA results, especially in younger men. Schedule the PSA test to be completed at least six weeks after undergoing any of the following procedures: prostate biopsy, transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH), urethral cancer, cystoscopy, or any other procedure that involves the prostate. If you are in doubt about the possible impact of any procedure on your PSA test, it is recommended that you speak with your physician. A PSA test should be scheduled you have a urinary tract infection (UTI). A bacterial infection in the urinary tract may cause PSA levels to elevate temporarily. If you are not sure if you have a UTI, have a urine test completed prior to the PSA test to confirm. If you are positive for a UTI, you should wait at least six weeks after antibiotic treatment has been completed before having the PSA test done. Schedule a DRE before the PSA test. Although a DRE should not have an impact on PSA levels, having a PSA test completed first is a precaution. It is important to tell your doctor: if you are undergoing chemotherapy, as these drugs may cause an elevated PSA level; if you are taking any medications such as statins, nonsteroidal anti-inflammatory drugs (NSAIDs), or medications that control urinary problems (dutasteride, finasteride, etc.). All of these substances have the potential to affect PSA levels; if you have undergone urinary tract or prostate surgery recently; if you have suffered pelvic surgery or sports injury; or if you have prostatitis or BPH.