Estrone, Serum LabCorp

Estrone (E1) is one of three estrogens, the other two being estriol and estradiol. Estrone is the least abundant of the three and is relevant to health and disease because it is considered the stronger acting estrogen. In post-menopausal women, however, higher levels of estrone when compared to the other estrogens have been implicated in cardiovascular disease, stroke, and certain types of cancer. If you are undergoing estrogen replacement therapy, it is important to monitor the balance of the three main estrogens in the body, Estrogen (E1), Estradiol (E2), and Estriol (E3). Imbalances in the relationship between estrone and the other two major estrogens are thought to increase the risk for many age-related diseases.