Fructosamine LabCorp

Fructosamine is tested in the evaluation of diabetic control, reflecting diabetic control over a shorter time period (1 to 3 weeks) than that represented by hemoglobin A1c (4 to 8 weeks). Indicated as an index of longer-term control than glucose levels, especially in diabetic subjects with abnormal hemoglobins and in type 1 diabetes in children. 

Frucotsamine is found int he plasma of both normal and diabetic individuals. "Fructosamine" is the term used to describe proteins that have been glycated (i.e., are derivatives of the noneynzymatic reaction product of glucose and albumin). It has been advocated as an alternative test to hemoglobin A1c for the monitoring of long-term diabetic control. Fructosamine and hemoglobin A1c do not measure exactly the same thing, since fructosamin ehas a shorter half-life and appears to be more sensitive to short-term variations in glucose levels; however, this is not necessarily a disadvantage. Fructosamin eis clearly superior in patients with abnormal hemoglobins because of the interference of abnormal hemoglobins in the anion-exchange chromatography methods for Hemoglobin A1c. 

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