Melasma TA Gel (Niacinamide / Tranexamic Acid / Tretinoin 4/4/0.03% 30 mL Pump)
Niacinamide 4%/ Tranexamic Acid 4%/ Tretinoin 0.03%
Niacin (nicotinic acid or 3-pyridinecarboxylic acid) is a B-complex vitamin. Good dietary sources of niacin are animal proteins, beans, green vegetables, liver, mushrooms, peanuts, whole wheat, and unpolished rice. Niacin is also present in cereal grains but is largely bound to plant proteins, and thus is poorly absorbed after ingestion.
Tranexamic acid is an oral and injectable antifibrinolytic agent indicated for short-term use to reduce or prevent hemorrhage and reduce the need for replacement therapy during and after tooth extraction in patients with hemophilia and for the treatment of cyclic heavy menstrual bleeding. Tranexamic acid may increase the risk of thromboembolic events. Venous and arterial thrombosis or thromboembolism have been reported in patients treated with tranexamic acid.
Topical tretinoin is indicated in the treatment of mild to moderate acne (e.g., grades I-III) and photodamaged skin. Topical tretinoin has also been used in the symptomatic management of keratinization disorders such as ichthyosis and keratosis follicularis.